Odd serendipity with other books I've recently read. The doctor inside Biosphere 2 discovered that insecticide toxins stored inside fat, like DDT and DDE, were released into the biospherians' bloodstreams as they metabolized their fat.
At the tail end of the 2 years, Ed Bass the funder fired the two principals John Allen and Margret Augustine because of financial improprieties. Guess who he brought in to straighten the books? Steve Bannon. Bannon immediately fired almost all the scientists on the project, destroyed all the data collected and brought in a bunch of investment bankers. Somehow he thought Biosphere 2 could be made into a moneymaking proposition.
No surprise then that the whole enterprise fell apart almost immediately afterward, and hasn't seen another habitation since.